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Foreign Filing Priority As mentioned above, it is the actual filing date of the first application at the USPTO that triggers the patent term, even if the application claims priority from an earlier-filed foreign application

The medication works by activating both GIP and GLP-1 receptors, enhancing insulin secretion in a glucose-dependent manner, suppressing glucagon release, slowing gastric emptying, and reducing appetite

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The combined effects of increased cytoplasmic monoamine availability and transporter phosphorylation cause reversal of transporter flux, resulting in non-exocytotic neurotransmitter efflux into the synaptic cleftthe characteristic one-two punch mechanism underlying amphetamine-induced monoamine release